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Lucas Liaudet Selected Research

Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)

11/2020Poly(ADP-Ribose) Polymerase Inhibition in Acute Lung Injury. A Reemerging Concept.
1/2020Effects of the Poly(ADP-Ribose) Polymerase Inhibitor Olaparib in Cerulein-Induced Pancreatitis.
1/2020Treatment with 3-aminobenzamide during ex vivo lung perfusion of damaged rat lungs reduces graft injury and dysfunction after transplantation.
1/2019The PARP inhibitor olaparib exerts beneficial effects in mice subjected to cecal ligature and puncture and in cells subjected to oxidative stress without impairing DNA integrity: A potential opportunity for repurposing a clinically used oncological drug for the experimental therapy of sepsis.
1/2018Chemo-manipulation of tumor blood vessels by a metal-based anticancer complex enhances antitumor therapy.
1/2016Pharmacological Reconditioning of Marginal Donor Rat Lungs Using Inhibitors of Peroxynitrite and Poly (ADP-ribose) Polymerase During Ex Vivo Lung Perfusion.
2/2015Poly(ADP-ribose) polymerases as modulators of mitochondrial activity.
1/2015Cannabidiol Protects against Doxorubicin-Induced Cardiomyopathy by Modulating Mitochondrial Function and Biogenesis.
1/2010Bacterial flagellin elicits widespread innate immune defense mechanisms, apoptotic signaling, and a sepsis-like systemic inflammatory response in mice.
8/2009Xanthine oxidase inhibitor allopurinol attenuates the development of diabetic cardiomyopathy.
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Lucas Liaudet Research Topics

Disease

32Inflammation (Inflammations)
01/2021 - 01/2002
20Shock
11/2021 - 03/2002
16Heart Failure
01/2022 - 09/2002
13Reperfusion Injury
01/2017 - 01/2002
12Sepsis (Septicemia)
01/2019 - 04/2002
10Ischemia
01/2021 - 01/2002
8Necrosis
01/2018 - 04/2002
7Fibrosis (Cirrhosis)
01/2017 - 08/2009
7Cardiotoxicity
11/2015 - 02/2003
6Heart Arrest (Cardiac Arrest)
11/2021 - 07/2006
6Septic Shock (Toxic Shock Syndrome)
01/2019 - 09/2010
6Neoplasms (Cancer)
01/2018 - 11/2006
6Hyperemia
02/2013 - 11/2003
6Atherosclerosis
03/2012 - 06/2002
5Edema (Dropsy)
07/2022 - 02/2002
5Infections
01/2020 - 09/2002
5Myocardial Infarction
01/2019 - 01/2007
5Diabetic Cardiomyopathies
02/2015 - 02/2006
4Cardiogenic Shock
11/2020 - 12/2012
4Critical Illness (Critically Ill)
04/2020 - 03/2002
4Infarction (Infarctions)
07/2015 - 02/2011
4Cardiomyopathies (Cardiomyopathy)
01/2015 - 03/2010
4Cardiovascular Diseases (Cardiovascular Disease)
01/2011 - 07/2008
4Peritonitis
09/2009 - 04/2002
4Stroke (Strokes)
08/2007 - 09/2002
4Pneumonia (Pneumonitis)
07/2007 - 02/2002
4Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
12/2004 - 04/2002
3Weight Gain
07/2022 - 01/2016
3Lung Injury
07/2022 - 02/2003
3Liver Diseases (Liver Disease)
01/2021 - 09/2012
3Mitochondrial Diseases (Mitochondrial Disease)
11/2015 - 11/2014
3Hyperglycemia
02/2015 - 02/2002
3Coma (Comas)
03/2012 - 07/2006
3Ventricular Fibrillation
08/2008 - 06/2004
3Hypertension (High Blood Pressure)
03/2008 - 06/2002
2COVID-19
06/2021 - 01/2020
2Acute Lung Injury
11/2020 - 04/2002

Drug/Important Bio-Agent (IBA)

23Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
11/2020 - 01/2002
15EnzymesIBA
11/2020 - 03/2002
14Poly(ADP-ribose) Polymerase InhibitorsIBA
01/2020 - 01/2002
14Peroxynitrous Acid (Peroxynitrite)IBA
03/2013 - 05/2002
13Oxygen (Dioxygen)IBA
07/2022 - 06/2002
11Proteins (Proteins, Gene)FDA Link
07/2022 - 02/2002
10Oxidants (Oxidizing Agents)IBA
02/2011 - 01/2002
9Interleukin-6 (Interleukin 6)IBA
07/2022 - 02/2002
9CytokinesIBA
01/2020 - 02/2002
83-nitrotyrosineIBA
07/2022 - 08/2009
8NitrogenIBA
01/2016 - 06/2002
8Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2011 - 02/2002
7Doxorubicin (Adriamycin)FDA LinkGeneric
01/2015 - 02/2003
7Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
07/2012 - 02/2002
6Messenger RNA (mRNA)IBA
01/2020 - 06/2005
6Pharmaceutical PreparationsIBA
01/2019 - 06/2004
6Acetylcholine (Acetylcholine Chloride)FDA Link
01/2008 - 03/2002
6LipopolysaccharidesIBA
02/2003 - 01/2002
6N- (oxo- 5,6- dihydrophenanthridin- 2- yl)- N,N- dimethylacetamide hydrochlorideIBA
12/2002 - 01/2002
5EndocannabinoidsIBA
01/2021 - 08/2007
5NF-kappa B (NF-kB)IBA
01/2017 - 04/2003
5Poly Adenosine Diphosphate RiboseIBA
01/2016 - 04/2002
5Phosphotransferases (Kinase)IBA
07/2015 - 08/2007
5Caspase 3 (Caspase-3)IBA
12/2010 - 09/2006
4ChemokinesIBA
01/2022 - 02/2002
4CannabidiolIBA
09/2016 - 12/2010
4CannabinoidsIBA
11/2015 - 12/2007
4Transcription Factors (Transcription Factor)IBA
02/2015 - 04/2003
4Poly (ADP-Ribose) Polymerase-1IBA
05/2014 - 02/2002
4EndotoxinsIBA
05/2011 - 05/2002
4FlagellinIBA
09/2010 - 01/2002
4Antineoplastic Agents (Antineoplastics)IBA
05/2009 - 02/2003
3Biomarkers (Surrogate Marker)IBA
07/2022 - 07/2012
3L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
07/2022 - 01/2015
3Norepinephrine (Noradrenaline)FDA LinkGeneric
04/2020 - 07/2017
3olaparibIBA
01/2020 - 01/2017
3Peroxidase (Myeloperoxidase)IBA
01/2020 - 02/2002
3Malondialdehyde (Propanedial)IBA
01/2020 - 05/2002
3CalciumIBA
12/2019 - 03/2008
3Vasodilator Agents (Vasodilators)IBA
12/2019 - 11/2003
3Toll-Like Receptors (Toll-Like Receptor)IBA
07/2015 - 01/2010
3Superoxides (Superoxide)IBA
02/2015 - 10/2002
3ProstaglandinsIBA
02/2013 - 06/2004
3CollagenIBA
12/2010 - 10/2002
2LigandsIBA
01/2022 - 09/2010
2HMGB1 Protein (HMG1)IBA
01/2021 - 02/2011
2Vasopressins (Vasopressin)IBA
04/2020 - 07/2005
2Interleukin-10 (Interleukin 10)IBA
01/2020 - 04/2002
2CatecholaminesIBA
12/2019 - 11/2014
2DiureticsIBA
12/2019 - 07/2005

Therapy/Procedure

18Therapeutics
11/2021 - 04/2002
8Ligation
01/2019 - 04/2002
6Critical Care (Surgical Intensive Care)
04/2020 - 07/2006
5Heart-Assist Devices
01/2022 - 12/2012
5Investigational Therapies (Experimental Therapy)
01/2020 - 09/2002
4Transplantation
01/2018 - 01/2016
4Induced Hypothermia
03/2012 - 07/2006
4Lasers (Laser)
01/2011 - 11/2003
3Warm Ischemia
01/2020 - 01/2016
3Heart Transplantation (Grafting, Heart)
02/2006 - 01/2002
2Cardiopulmonary Resuscitation (CPR)
11/2021 - 06/2004
2Extracorporeal Membrane Oxygenation
11/2020 - 01/2020
2Catheters
07/2019 - 09/2016